Gene name:
Coro1a (Coro1) ;
Protein name:
Coronin-1A ;
Alternative:
Coronin-like protein p57 ;Coronin-like protein A (Clipin-A) ;Tryptophan aspartate-containing coat protein (TACO) ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.
Subcellular Location:
Cytoplasm
cytoskeleton
Cytoplasm
cell cortex
Cytoplasmic vesicle
phagosome membrane
In non-infected macrophages, associated with the cortical microtubule network. In mycobacteria-infected macrophages, becomes progressively relocalized and retained around the mycobacterial phagosomes. Retention on the phagosomal membrane is strictly dependent on mycobacterial viability and not due to impaired acidification.
Protein Attributes:
50:
MSRQVVRSSK | FRHVFGQPAK | ADQCYEDVRV | SQTTWDSGFC | AVNPKFMALI |
100:
CEASGGGAFL | VLPLGKTGRV | DKNVPLVCGH | TAPVLDIAWC | PHNDNVIASG |
150:
SEDCTVMVWE | IPDGGLVLPL | REPVITLEGH | TKRVGIVAWH | PTAQNVLLSA |
200:
GCDNVILVWD | VGTGAAVLTL | GPDVHPDTIY | SVDWSRDGAL | ICTSCRDKRV |
250:
RVIEPRKGTV | VAEKDRPHEG | TRPVHAVFVS | EGKILTTGFS | RMSERQVALW |
300:
DTKHLEEPLS | LQELDTSSGV | LLPFFDPDTN | IVYLCGKGDS | SIRYFEITSE |
350:
APFLHYLSMF | SSKESQRGMG | YMPKRGLEVN | KCEIARFYKL | HERKCEPIAM |
400:
TVPRKSDLFQ | EDLYPPTAGP | DPALTAEEWL | GGRDAGPLLI | SLKDGYVPPK |
450:
SRELRVNRGL | DSARRRATPE | PSGTPSSDTV | SRLEEDVRNL | NAIVQKLQER |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
Bovine
ELISA Kit for Mouse Coronin-1A
ELISA Kit for Mouse Coronin-1A
ELISA Kit for Mouse Coronin-1A
ELISA Kit for Mouse Coronin-1A
CLIA Kit for Mouse Coronin-1A
CLIA Kit for Mouse Coronin-1A
CLIA Kit for Mouse Coronin-1A
CLIA Kit for Mouse Coronin-1A
Polyclonal Antibody for Mouse Coronin-1A
Polyclonal Antibody for Mouse Coronin-1A
Polyclonal Antibody for Mouse Coronin-1A
Polyclonal Antibody for Mouse Coronin-1A
Monoclonal Antibody for Mouse Coronin-1A
Monoclonal Antibody for Mouse Coronin-1A
Monoclonal Antibody for Mouse Coronin-1A
Monoclonal Antibody for Mouse Coronin-1A
Protein for Mouse Coronin-1A
Protein for Mouse Coronin-1A
Protein for Mouse Coronin-1A
Protein for Mouse Coronin-1A
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 11-14;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;ROLE IN PHAGOSOME TRAFFICKING
strain :
C57BL/6 .
tissue :
Macrophage .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Hematopoietic .
tissue :
Mammary tumor .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 156-276
strain :
BALB/c .
tissue :
Spleen .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 215-233;IDENTIFICATION BY MASS SPECTROMETRY
tissue :
Hippocampus .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-418;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION AT SER-412
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.2 ANGSTROMS) OF 430-461;COILED-COIL DOMAIN
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS) OF 1-402;WD REPEATS;COILED-COIL DOMAIN